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Zambesil Brand names, Zambesil Analogs

Zambesil Brand Names Mixture

  • Tenoretic (chlorthalidone + atenolol)

Zambesil Chemical_Formula


Zambesil RX_link

Zambesil fda sheet

Zambesil msds (material safety sheet)

Zambesil Synthesis Reference

Graf et al.; Helv. Chem.; Acta 42; 1085 (1959); U.S.Pat.3,055,904 (1962)

Zambesil Molecular Weight

338.767 g/mol

Zambesil Melting Point


Zambesil H2O Solubility

120 mg/L

Zambesil State


Zambesil LogP


Zambesil Dosage Forms


Zambesil Indication

For management of hypertension either as the sole therapeutic agent or to enhance the effect of other antihypertensive drugs in the more severe forms of hypertension.

Zambesil Pharmacology

Chlorthalidone, a monosulfonamyl diuretic, differs form other thiazide diuretics in that a double ring system is incorporated into its structure. Chlorthalidone is used alone or with atenolol in the management of hypertension and edema.

Zambesil Absorption

Absorbed relatively rapidly after oral administration.

Zambesil side effects and Toxicity

Symptoms of overdose include nausea, weakness, dizziness and disturbances of electrolyte balance.

Zambesil Patient Information

Patients should inform their physician if they have: (1) had an allergic reaction to chlorthalidone or other diuretics or have asthma, (2) kidney disease, (3) liver disease, (4) gout, (5) systemic lupus erythematosus, or (6) been taking other drugs such as cortisone, digitalis, lithium carbonate, or drugs for diabetes.

Patients should be cautioned to contact their physician if they experience any of the following symptoms of potassium loss: excess thirst, tiredness, drowsiness, restlessness, muscle pains or cramps, nausea, vomiting, or increased heart rate or pulse.

Patients should also be cautioned that taking alcohol can increase the chance of dizziness occurring.

Zambesil Organisms Affected

Humans and other mammals