Phthalamodine

Phthalamodine Brand names, Phthalamodine Analogs

Phthalamodine Brand Names Mixture

Tenoretic (chlorthalidone + atenolol)

Phthalamodine Chemical_Formula

C₁₄H₁₁ClN₂O₄S

Phthalamodine RX_link

http://www.rxlist.com/cgi/generic3/chlorthalidone.htm

Phthalamodine fda sheet

Phthalamodine msds (material safety sheet)

Phthalamodine Synthesis Reference

Graf et al.; Helv. Chem.; Acta 42; 1085 (1959); U.S.Pat.3,055,904 (1962)

Phthalamodine Molecular Weight

338.767 g/mol

Phthalamodine Melting Point

218-264^oC

Phthalamodine H₂O Solubility

120 mg/L

Phthalamodine State

Solid

Phthalamodine LogP

1.718

Phthalamodine Dosage Forms

Tablet

Phthalamodine Indication

For management of hypertension either as the sole therapeutic agent or to enhance the effect of other antihypertensive drugs in the more severe forms of hypertension.

Phthalamodine Pharmacology

Chlorthalidone, a monosulfonamyl diuretic, differs form other thiazide diuretics in that a double ring system is incorporated into its structure. Chlorthalidone is used alone or with atenolol in the management of hypertension and edema.

Phthalamodine Absorption

Absorbed relatively rapidly after oral administration.

Phthalamodine side effects and Toxicity

Symptoms of overdose include nausea, weakness, dizziness and disturbances of electrolyte balance.

Phthalamodine Patient Information

Patients should inform their physician if they have: (1) had an allergic reaction to chlorthalidone or other diuretics or have asthma, (2) kidney disease, (3) liver disease, (4) gout, (5) systemic lupus erythematosus, or (6) been taking other drugs such as cortisone, digitalis, lithium carbonate, or drugs for diabetes.

Patients should be cautioned to contact their physician if they experience any of the following symptoms of potassium loss: excess thirst, tiredness, drowsiness, restlessness, muscle pains or cramps, nausea, vomiting, or increased heart rate or pulse.

Patients should also be cautioned that taking alcohol can increase the chance of dizziness occurring.

Phthalamodine Organisms Affected

Humans and other mammals