Chlortalidone

Chlortalidone Brand names, Chlortalidone Analogs

Chlortalidone Brand Names Mixture

Tenoretic (chlorthalidone + atenolol)

Chlortalidone Chemical_Formula

C₁₄H₁₁ClN₂O₄S

Chlortalidone RX_link

http://www.rxlist.com/cgi/generic3/chlorthalidone.htm

Chlortalidone fda sheet

Chlortalidone msds (material safety sheet)

Chlortalidone Synthesis Reference

Graf et al.; Helv. Chem.; Acta 42; 1085 (1959); U.S.Pat.3,055,904 (1962)

Chlortalidone Molecular Weight

338.767 g/mol

Chlortalidone Melting Point

218-264^oC

Chlortalidone H₂O Solubility

120 mg/L

Chlortalidone State

Solid

Chlortalidone LogP

1.718

Chlortalidone Dosage Forms

Tablet

Chlortalidone Indication

For management of hypertension either as the sole therapeutic agent or to enhance the effect of other antihypertensive drugs in the more severe forms of hypertension.

Chlortalidone Pharmacology

Chlorthalidone, a monosulfonamyl diuretic, differs form other thiazide diuretics in that a double ring system is incorporated into its structure. Chlorthalidone is used alone or with atenolol in the management of hypertension and edema.

Chlortalidone Absorption

Absorbed relatively rapidly after oral administration.

Chlortalidone side effects and Toxicity

Symptoms of overdose include nausea, weakness, dizziness and disturbances of electrolyte balance.

Chlortalidone Patient Information

Patients should inform their physician if they have: (1) had an allergic reaction to chlorthalidone or other diuretics or have asthma, (2) kidney disease, (3) liver disease, (4) gout, (5) systemic lupus erythematosus, or (6) been taking other drugs such as cortisone, digitalis, lithium carbonate, or drugs for diabetes.

Patients should be cautioned to contact their physician if they experience any of the following symptoms of potassium loss: excess thirst, tiredness, drowsiness, restlessness, muscle pains or cramps, nausea, vomiting, or increased heart rate or pulse.

Patients should also be cautioned that taking alcohol can increase the chance of dizziness occurring.

Chlortalidone Organisms Affected

Humans and other mammals