Phthalamudine

Phthalamudine Brand names, Phthalamudine Analogs

Phthalamudine Brand Names Mixture

Tenoretic (chlorthalidone + atenolol)

Phthalamudine Chemical_Formula

C₁₄H₁₁ClN₂O₄S

Phthalamudine RX_link

http://www.rxlist.com/cgi/generic3/chlorthalidone.htm

Phthalamudine fda sheet

Phthalamudine msds (material safety sheet)

Phthalamudine Synthesis Reference

Graf et al.; Helv. Chem.; Acta 42; 1085 (1959); U.S.Pat.3,055,904 (1962)

Phthalamudine Molecular Weight

338.767 g/mol

Phthalamudine Melting Point

218-264^oC

Phthalamudine H₂O Solubility

120 mg/L

Phthalamudine State

Solid

Phthalamudine LogP

1.718

Phthalamudine Dosage Forms

Tablet

Phthalamudine Indication

For management of hypertension either as the sole therapeutic agent or to enhance the effect of other antihypertensive drugs in the more severe forms of hypertension.

Phthalamudine Pharmacology

Chlorthalidone, a monosulfonamyl diuretic, differs form other thiazide diuretics in that a double ring system is incorporated into its structure. Chlorthalidone is used alone or with atenolol in the management of hypertension and edema.

Phthalamudine Absorption

Absorbed relatively rapidly after oral administration.

Phthalamudine side effects and Toxicity

Symptoms of overdose include nausea, weakness, dizziness and disturbances of electrolyte balance.

Phthalamudine Patient Information

Patients should inform their physician if they have: (1) had an allergic reaction to chlorthalidone or other diuretics or have asthma, (2) kidney disease, (3) liver disease, (4) gout, (5) systemic lupus erythematosus, or (6) been taking other drugs such as cortisone, digitalis, lithium carbonate, or drugs for diabetes.

Patients should be cautioned to contact their physician if they experience any of the following symptoms of potassium loss: excess thirst, tiredness, drowsiness, restlessness, muscle pains or cramps, nausea, vomiting, or increased heart rate or pulse.

Patients should also be cautioned that taking alcohol can increase the chance of dizziness occurring.

Phthalamudine Organisms Affected

Humans and other mammals