Chlorthalidon

Chlorthalidon Brand names, Chlorthalidon Analogs

Chlorthalidon Brand Names Mixture

Tenoretic (chlorthalidone + atenolol)

Chlorthalidon Chemical_Formula

C₁₄H₁₁ClN₂O₄S

Chlorthalidon RX_link

http://www.rxlist.com/cgi/generic3/chlorthalidone.htm

Chlorthalidon fda sheet

Chlorthalidon msds (material safety sheet)

Chlorthalidon Synthesis Reference

Graf et al.; Helv. Chem.; Acta 42; 1085 (1959); U.S.Pat.3,055,904 (1962)

Chlorthalidon Molecular Weight

338.767 g/mol

Chlorthalidon Melting Point

218-264^oC

Chlorthalidon H₂O Solubility

120 mg/L

Chlorthalidon State

Solid

Chlorthalidon LogP

1.718

Chlorthalidon Dosage Forms

Tablet

Chlorthalidon Indication

For management of hypertension either as the sole therapeutic agent or to enhance the effect of other antihypertensive drugs in the more severe forms of hypertension.

Chlorthalidon Pharmacology

Chlorthalidone, a monosulfonamyl diuretic, differs form other thiazide diuretics in that a double ring system is incorporated into its structure. Chlorthalidone is used alone or with atenolol in the management of hypertension and edema.

Chlorthalidon Absorption

Absorbed relatively rapidly after oral administration.

Chlorthalidon side effects and Toxicity

Symptoms of overdose include nausea, weakness, dizziness and disturbances of electrolyte balance.

Chlorthalidon Patient Information

Patients should inform their physician if they have: (1) had an allergic reaction to chlorthalidone or other diuretics or have asthma, (2) kidney disease, (3) liver disease, (4) gout, (5) systemic lupus erythematosus, or (6) been taking other drugs such as cortisone, digitalis, lithium carbonate, or drugs for diabetes.

Patients should be cautioned to contact their physician if they experience any of the following symptoms of potassium loss: excess thirst, tiredness, drowsiness, restlessness, muscle pains or cramps, nausea, vomiting, or increased heart rate or pulse.

Patients should also be cautioned that taking alcohol can increase the chance of dizziness occurring.

Chlorthalidon Organisms Affected

Humans and other mammals