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Acyclovir Brand names, Acyclovir Analogs

Acyclovir Brand Names Mixture

  • Zovirax Injection (Zovirax sodium)

Acyclovir Chemical_Formula


Acyclovir RX_link

Acyclovir fda sheet

Acyclovir FDA

Acyclovir msds (material safety sheet)

Acyclovir MSDS

Acyclovir Synthesis Reference

H. Matsumoto et al., Chem. Pharm. Bull. 35, 1153 (1988)

Acyclovir Molecular Weight

225.205 g/mol

Acyclovir Melting Point

256.5 - 257 oC

Acyclovir H2O Solubility

3.399 mg/L

Acyclovir State


Acyclovir LogP


Acyclovir Dosage Forms

Intravenous infusion; Capsule; Tablet; Suspension; Topical cream; Topical ointment

Acyclovir Indication

For the treatment and management of herpes zoster (shingles), genital herpes, and chickenpox

Acyclovir Pharmacology

Acyclovir is a synthetic deoxyguanosine analog and it is the prototype antiviral agent that is activated by viral thymidine kinase. The selective activity of acyclovir is due to its affinity for the thymidine kinase enzyme encoded by HSV and VZV.

Acyclovir Absorption

Oral: bioavailability 10 to 20%

Acyclovir side effects and Toxicity

Acyclovir may cause nephrotoxicity (crystallization of acyclovir within renal tubules, elevation of serum creatinine, transient), and neurotoxicity (coma, hallucinations, lethargy, seizures, tremors). Nephrotoxicity and neurotoxicity usually resolve after cessation of acyclovir therapy. However, there is no well-defined relationship between acyclovir concentrations in the blood and these adverse effects.

Acyclovir Patient Information

Acyclovir Organisms Affected

Human herpes virus