Zovirax
Zovirax Brand names, Zovirax Analogs
Zovirax Brand Names Mixture
- Zovirax Injection (Zovirax sodium)
Zovirax Chemical_Formula
C8H11N5O3
Zovirax RX_link
http://www.rxlist.com/cgi/generic/acyclo.htm
Zovirax fda sheet
Zovirax msds (material safety sheet)
Zovirax Synthesis Reference
H. Matsumoto et al., Chem. Pharm. Bull. 35, 1153 (1988)
Zovirax Molecular Weight
225.205 g/mol
Zovirax Melting Point
256.5 - 257 oC
Zovirax H2O Solubility
3.399 mg/L
Zovirax State
Solid
Zovirax LogP
-1.314
Zovirax Dosage Forms
Intravenous infusion; Capsule; Tablet; Suspension; Topical cream; Topical ointment
Zovirax Indication
For the treatment and management of herpes zoster (shingles), genital herpes, and chickenpox
Zovirax Pharmacology
Acyclovir is a synthetic deoxyguanosine analog and it is the prototype antiviral agent that is activated by viral thymidine kinase. The selective activity of acyclovir is due to its affinity for the thymidine kinase enzyme encoded by HSV and VZV.
Zovirax Absorption
Oral: bioavailability 10 to 20%
Zovirax side effects and Toxicity
Acyclovir may cause nephrotoxicity (crystallization of acyclovir within renal tubules, elevation of serum creatinine, transient), and neurotoxicity (coma, hallucinations, lethargy, seizures, tremors). Nephrotoxicity and neurotoxicity usually resolve after cessation of acyclovir therapy. However, there is no well-defined relationship between acyclovir concentrations in the blood and these adverse effects.
Zovirax Patient Information
Zovirax Organisms Affected
Human herpes virus
