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Zovirax Brand names, Zovirax Analogs

Zovirax Brand Names Mixture

  • Zovirax Injection (Zovirax sodium)

Zovirax Chemical_Formula

C8H11N5O3

Zovirax RX_link

http://www.rxlist.com/cgi/generic/acyclo.htm

Zovirax fda sheet

Zovirax FDA

Zovirax msds (material safety sheet)

Zovirax MSDS

Zovirax Synthesis Reference

H. Matsumoto et al., Chem. Pharm. Bull. 35, 1153 (1988)

Zovirax Molecular Weight

225.205 g/mol

Zovirax Melting Point

256.5 - 257 oC

Zovirax H2O Solubility

3.399 mg/L

Zovirax State

Solid

Zovirax LogP

-1.314

Zovirax Dosage Forms

Intravenous infusion; Capsule; Tablet; Suspension; Topical cream; Topical ointment

Zovirax Indication

For the treatment and management of herpes zoster (shingles), genital herpes, and chickenpox

Zovirax Pharmacology

Acyclovir is a synthetic deoxyguanosine analog and it is the prototype antiviral agent that is activated by viral thymidine kinase. The selective activity of acyclovir is due to its affinity for the thymidine kinase enzyme encoded by HSV and VZV.

Zovirax Absorption

Oral: bioavailability 10 to 20%

Zovirax side effects and Toxicity

Acyclovir may cause nephrotoxicity (crystallization of acyclovir within renal tubules, elevation of serum creatinine, transient), and neurotoxicity (coma, hallucinations, lethargy, seizures, tremors). Nephrotoxicity and neurotoxicity usually resolve after cessation of acyclovir therapy. However, there is no well-defined relationship between acyclovir concentrations in the blood and these adverse effects.

Zovirax Patient Information

Zovirax Organisms Affected

Human herpes virus