Valtrex
Valtrex Brand names, Valtrex Analogs
Valtrex Brand Names Mixture
- Zovirax Injection (Zovirax sodium)
Valtrex Chemical_Formula
C8H11N5O3
Valtrex RX_link
http://www.rxlist.com/cgi/generic/acyclo.htm
Valtrex fda sheet
Valtrex msds (material safety sheet)
Valtrex Synthesis Reference
H. Matsumoto et al., Chem. Pharm. Bull. 35, 1153 (1988)
Valtrex Molecular Weight
225.205 g/mol
Valtrex Melting Point
256.5 - 257 oC
Valtrex H2O Solubility
3.399 mg/L
Valtrex State
Solid
Valtrex LogP
-1.314
Valtrex Dosage Forms
Intravenous infusion; Capsule; Tablet; Suspension; Topical cream; Topical ointment
Valtrex Indication
For the treatment and management of herpes zoster (shingles), genital herpes, and chickenpox
Valtrex Pharmacology
Acyclovir is a synthetic deoxyguanosine analog and it is the prototype antiviral agent that is activated by viral thymidine kinase. The selective activity of acyclovir is due to its affinity for the thymidine kinase enzyme encoded by HSV and VZV.
Valtrex Absorption
Oral: bioavailability 10 to 20%
Valtrex side effects and Toxicity
Acyclovir may cause nephrotoxicity (crystallization of acyclovir within renal tubules, elevation of serum creatinine, transient), and neurotoxicity (coma, hallucinations, lethargy, seizures, tremors). Nephrotoxicity and neurotoxicity usually resolve after cessation of acyclovir therapy. However, there is no well-defined relationship between acyclovir concentrations in the blood and these adverse effects.
Valtrex Patient Information
Valtrex Organisms Affected
Human herpes virus
