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Virorax Brand names, Virorax Analogs

Virorax Brand Names Mixture

  • Zovirax Injection (Zovirax sodium)

Virorax Chemical_Formula

C8H11N5O3

Virorax RX_link

http://www.rxlist.com/cgi/generic/acyclo.htm

Virorax fda sheet

Virorax FDA

Virorax msds (material safety sheet)

Virorax MSDS

Virorax Synthesis Reference

H. Matsumoto et al., Chem. Pharm. Bull. 35, 1153 (1988)

Virorax Molecular Weight

225.205 g/mol

Virorax Melting Point

256.5 - 257 oC

Virorax H2O Solubility

3.399 mg/L

Virorax State

Solid

Virorax LogP

-1.314

Virorax Dosage Forms

Intravenous infusion; Capsule; Tablet; Suspension; Topical cream; Topical ointment

Virorax Indication

For the treatment and management of herpes zoster (shingles), genital herpes, and chickenpox

Virorax Pharmacology

Acyclovir is a synthetic deoxyguanosine analog and it is the prototype antiviral agent that is activated by viral thymidine kinase. The selective activity of acyclovir is due to its affinity for the thymidine kinase enzyme encoded by HSV and VZV.

Virorax Absorption

Oral: bioavailability 10 to 20%

Virorax side effects and Toxicity

Acyclovir may cause nephrotoxicity (crystallization of acyclovir within renal tubules, elevation of serum creatinine, transient), and neurotoxicity (coma, hallucinations, lethargy, seizures, tremors). Nephrotoxicity and neurotoxicity usually resolve after cessation of acyclovir therapy. However, there is no well-defined relationship between acyclovir concentrations in the blood and these adverse effects.

Virorax Patient Information

Virorax Organisms Affected

Human herpes virus