Virorax
Virorax Brand names, Virorax Analogs
Virorax Brand Names Mixture
- Zovirax Injection (Zovirax sodium)
Virorax Chemical_Formula
C8H11N5O3
Virorax RX_link
http://www.rxlist.com/cgi/generic/acyclo.htm
Virorax fda sheet
Virorax msds (material safety sheet)
Virorax Synthesis Reference
H. Matsumoto et al., Chem. Pharm. Bull. 35, 1153 (1988)
Virorax Molecular Weight
225.205 g/mol
Virorax Melting Point
256.5 - 257 oC
Virorax H2O Solubility
3.399 mg/L
Virorax State
Solid
Virorax LogP
-1.314
Virorax Dosage Forms
Intravenous infusion; Capsule; Tablet; Suspension; Topical cream; Topical ointment
Virorax Indication
For the treatment and management of herpes zoster (shingles), genital herpes, and chickenpox
Virorax Pharmacology
Acyclovir is a synthetic deoxyguanosine analog and it is the prototype antiviral agent that is activated by viral thymidine kinase. The selective activity of acyclovir is due to its affinity for the thymidine kinase enzyme encoded by HSV and VZV.
Virorax Absorption
Oral: bioavailability 10 to 20%
Virorax side effects and Toxicity
Acyclovir may cause nephrotoxicity (crystallization of acyclovir within renal tubules, elevation of serum creatinine, transient), and neurotoxicity (coma, hallucinations, lethargy, seizures, tremors). Nephrotoxicity and neurotoxicity usually resolve after cessation of acyclovir therapy. However, there is no well-defined relationship between acyclovir concentrations in the blood and these adverse effects.
Virorax Patient Information
Virorax Organisms Affected
Human herpes virus
