Acyclovir Sodium
Acyclovir Sodium Brand names, Acyclovir Sodium Analogs
Acyclovir Sodium Brand Names Mixture
- Zovirax Injection (Zovirax sodium)
Acyclovir Sodium Chemical_Formula
C8H11N5O3
Acyclovir Sodium RX_link
http://www.rxlist.com/cgi/generic/acyclo.htm
Acyclovir Sodium fda sheet
Acyclovir Sodium msds (material safety sheet)
Acyclovir Sodium Synthesis Reference
H. Matsumoto et al., Chem. Pharm. Bull. 35, 1153 (1988)
Acyclovir Sodium Molecular Weight
225.205 g/mol
Acyclovir Sodium Melting Point
256.5 - 257 oC
Acyclovir Sodium H2O Solubility
3.399 mg/L
Acyclovir Sodium State
Solid
Acyclovir Sodium LogP
-1.314
Acyclovir Sodium Dosage Forms
Intravenous infusion; Capsule; Tablet; Suspension; Topical cream; Topical ointment
Acyclovir Sodium Indication
For the treatment and management of herpes zoster (shingles), genital herpes, and chickenpox
Acyclovir Sodium Pharmacology
Acyclovir is a synthetic deoxyguanosine analog and it is the prototype antiviral agent that is activated by viral thymidine kinase. The selective activity of acyclovir is due to its affinity for the thymidine kinase enzyme encoded by HSV and VZV.
Acyclovir Sodium Absorption
Oral: bioavailability 10 to 20%
Acyclovir Sodium side effects and Toxicity
Acyclovir may cause nephrotoxicity (crystallization of acyclovir within renal tubules, elevation of serum creatinine, transient), and neurotoxicity (coma, hallucinations, lethargy, seizures, tremors). Nephrotoxicity and neurotoxicity usually resolve after cessation of acyclovir therapy. However, there is no well-defined relationship between acyclovir concentrations in the blood and these adverse effects.
Acyclovir Sodium Patient Information
Acyclovir Sodium Organisms Affected
Human herpes virus
