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Aciclovir Brand names, Aciclovir Analogs

Aciclovir Brand Names Mixture

  • Zovirax Injection (Zovirax sodium)

Aciclovir Chemical_Formula


Aciclovir RX_link

Aciclovir fda sheet

Aciclovir FDA

Aciclovir msds (material safety sheet)

Aciclovir MSDS

Aciclovir Synthesis Reference

H. Matsumoto et al., Chem. Pharm. Bull. 35, 1153 (1988)

Aciclovir Molecular Weight

225.205 g/mol

Aciclovir Melting Point

256.5 - 257 oC

Aciclovir H2O Solubility

3.399 mg/L

Aciclovir State


Aciclovir LogP


Aciclovir Dosage Forms

Intravenous infusion; Capsule; Tablet; Suspension; Topical cream; Topical ointment

Aciclovir Indication

For the treatment and management of herpes zoster (shingles), genital herpes, and chickenpox

Aciclovir Pharmacology

Acyclovir is a synthetic deoxyguanosine analog and it is the prototype antiviral agent that is activated by viral thymidine kinase. The selective activity of acyclovir is due to its affinity for the thymidine kinase enzyme encoded by HSV and VZV.

Aciclovir Absorption

Oral: bioavailability 10 to 20%

Aciclovir side effects and Toxicity

Acyclovir may cause nephrotoxicity (crystallization of acyclovir within renal tubules, elevation of serum creatinine, transient), and neurotoxicity (coma, hallucinations, lethargy, seizures, tremors). Nephrotoxicity and neurotoxicity usually resolve after cessation of acyclovir therapy. However, there is no well-defined relationship between acyclovir concentrations in the blood and these adverse effects.

Aciclovir Patient Information

Aciclovir Organisms Affected

Human herpes virus