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Aciclovier Brand names, Aciclovier Analogs

Aciclovier Brand Names Mixture

  • Zovirax Injection (Zovirax sodium)

Aciclovier Chemical_Formula


Aciclovier RX_link

Aciclovier fda sheet

Aciclovier FDA

Aciclovier msds (material safety sheet)

Aciclovier MSDS

Aciclovier Synthesis Reference

H. Matsumoto et al., Chem. Pharm. Bull. 35, 1153 (1988)

Aciclovier Molecular Weight

225.205 g/mol

Aciclovier Melting Point

256.5 - 257 oC

Aciclovier H2O Solubility

3.399 mg/L

Aciclovier State


Aciclovier LogP


Aciclovier Dosage Forms

Intravenous infusion; Capsule; Tablet; Suspension; Topical cream; Topical ointment

Aciclovier Indication

For the treatment and management of herpes zoster (shingles), genital herpes, and chickenpox

Aciclovier Pharmacology

Acyclovir is a synthetic deoxyguanosine analog and it is the prototype antiviral agent that is activated by viral thymidine kinase. The selective activity of acyclovir is due to its affinity for the thymidine kinase enzyme encoded by HSV and VZV.

Aciclovier Absorption

Oral: bioavailability 10 to 20%

Aciclovier side effects and Toxicity

Acyclovir may cause nephrotoxicity (crystallization of acyclovir within renal tubules, elevation of serum creatinine, transient), and neurotoxicity (coma, hallucinations, lethargy, seizures, tremors). Nephrotoxicity and neurotoxicity usually resolve after cessation of acyclovir therapy. However, there is no well-defined relationship between acyclovir concentrations in the blood and these adverse effects.

Aciclovier Patient Information

Aciclovier Organisms Affected

Human herpes virus