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AC2 Brand names, AC2 Analogs

AC2 Brand Names Mixture

  • Zovirax Injection (Zovirax sodium)

AC2 Chemical_Formula


AC2 RX_link

AC2 fda sheet


AC2 msds (material safety sheet)


AC2 Synthesis Reference

H. Matsumoto et al., Chem. Pharm. Bull. 35, 1153 (1988)

AC2 Molecular Weight

225.205 g/mol

AC2 Melting Point

256.5 - 257 oC

AC2 H2O Solubility

3.399 mg/L

AC2 State


AC2 LogP


AC2 Dosage Forms

Intravenous infusion; Capsule; Tablet; Suspension; Topical cream; Topical ointment

AC2 Indication

For the treatment and management of herpes zoster (shingles), genital herpes, and chickenpox

AC2 Pharmacology

Acyclovir is a synthetic deoxyguanosine analog and it is the prototype antiviral agent that is activated by viral thymidine kinase. The selective activity of acyclovir is due to its affinity for the thymidine kinase enzyme encoded by HSV and VZV.

AC2 Absorption

Oral: bioavailability 10 to 20%

AC2 side effects and Toxicity

Acyclovir may cause nephrotoxicity (crystallization of acyclovir within renal tubules, elevation of serum creatinine, transient), and neurotoxicity (coma, hallucinations, lethargy, seizures, tremors). Nephrotoxicity and neurotoxicity usually resolve after cessation of acyclovir therapy. However, there is no well-defined relationship between acyclovir concentrations in the blood and these adverse effects.

AC2 Patient Information

AC2 Organisms Affected

Human herpes virus