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Acycloguanosine Brand names, Acycloguanosine Analogs

Acycloguanosine Brand Names Mixture

  • Zovirax Injection (Zovirax sodium)

Acycloguanosine Chemical_Formula


Acycloguanosine RX_link

Acycloguanosine fda sheet

Acycloguanosine FDA

Acycloguanosine msds (material safety sheet)

Acycloguanosine MSDS

Acycloguanosine Synthesis Reference

H. Matsumoto et al., Chem. Pharm. Bull. 35, 1153 (1988)

Acycloguanosine Molecular Weight

225.205 g/mol

Acycloguanosine Melting Point

256.5 - 257 oC

Acycloguanosine H2O Solubility

3.399 mg/L

Acycloguanosine State


Acycloguanosine LogP


Acycloguanosine Dosage Forms

Intravenous infusion; Capsule; Tablet; Suspension; Topical cream; Topical ointment

Acycloguanosine Indication

For the treatment and management of herpes zoster (shingles), genital herpes, and chickenpox

Acycloguanosine Pharmacology

Acyclovir is a synthetic deoxyguanosine analog and it is the prototype antiviral agent that is activated by viral thymidine kinase. The selective activity of acyclovir is due to its affinity for the thymidine kinase enzyme encoded by HSV and VZV.

Acycloguanosine Absorption

Oral: bioavailability 10 to 20%

Acycloguanosine side effects and Toxicity

Acyclovir may cause nephrotoxicity (crystallization of acyclovir within renal tubules, elevation of serum creatinine, transient), and neurotoxicity (coma, hallucinations, lethargy, seizures, tremors). Nephrotoxicity and neurotoxicity usually resolve after cessation of acyclovir therapy. However, there is no well-defined relationship between acyclovir concentrations in the blood and these adverse effects.

Acycloguanosine Patient Information

Acycloguanosine Organisms Affected

Human herpes virus