Sirprogen
Category
Sirprogen Brand names, Sirprogen Analogs
Sirprogen Brand Names Mixture
Lunelle (Medroxyprogesterone + Estradiol)
Sirprogen Chemical_Formula
C22H32O3
Sirprogen RX_link
http://www.rxlist.com/cgi/generic/medrox.htm
Sirprogen fda sheet
Sirprogen msds (material safety sheet)
Sirprogen Synthesis Reference
P. Ruggieri, C. Ferrari, U.S. Pat. 3,043,832 (1962)
Sirprogen Molecular Weight
344.488 g/mol
Sirprogen Melting Point
220 - 223.5 oC
Sirprogen H2O Solubility
22.2mg/L
Sirprogen State
Solid
Sirprogen LogP
3.606
Sirprogen Dosage Forms
Tablets; Depo injection
Sirprogen Indication
Used as a contraceptive and to treat amenorrhea, abnormal uterine bleeding, endometriosis, endometrial and renal cell carcinomas, and pulmonary disorders such as chronic obstructive pulmonary disease (COPD), Pickwickian syndrome, and other hypercapnic pulmonary conditions.
Sirprogen Pharmacology
Medroxyprogesterone is a synthetic progestin more potent than progesterone.
Sirprogen Absorption
Rapidly absorbed from GI tract
Sirprogen Toxicity
Side effects include loss of bone mineral density, BMD changes in adult women, bleeding irregularities, cancer risks, and thromboembolic disorders.
Sirprogen Patient Information
Sirprogen Organisms Affected
Humans and other mammals