Depo-Progestin
Category
Depo-Progestin Brand names, Depo-Progestin Analogs
Depo-Progestin Brand Names Mixture
Lunelle (Medroxyprogesterone + Estradiol)
Depo-Progestin Chemical_Formula
C22H32O3
Depo-Progestin RX_link
http://www.rxlist.com/cgi/generic/medrox.htm
Depo-Progestin fda sheet
Depo-Progestin msds (material safety sheet)
Depo-Progestin Synthesis Reference
P. Ruggieri, C. Ferrari, U.S. Pat. 3,043,832 (1962)
Depo-Progestin Molecular Weight
344.488 g/mol
Depo-Progestin Melting Point
220 - 223.5 oC
Depo-Progestin H2O Solubility
22.2mg/L
Depo-Progestin State
Solid
Depo-Progestin LogP
3.606
Depo-Progestin Dosage Forms
Tablets; Depo injection
Depo-Progestin Indication
Used as a contraceptive and to treat amenorrhea, abnormal uterine bleeding, endometriosis, endometrial and renal cell carcinomas, and pulmonary disorders such as chronic obstructive pulmonary disease (COPD), Pickwickian syndrome, and other hypercapnic pulmonary conditions.
Depo-Progestin Pharmacology
Medroxyprogesterone is a synthetic progestin more potent than progesterone.
Depo-Progestin Absorption
Rapidly absorbed from GI tract
Depo-Progestin Toxicity
Side effects include loss of bone mineral density, BMD changes in adult women, bleeding irregularities, cancer risks, and thromboembolic disorders.
Depo-Progestin Patient Information
Depo-Progestin Organisms Affected
Humans and other mammals
