Medroxyprogesteron_acetate
Category
Medroxyprogesteron_acetate Brand names, Medroxyprogesteron_acetate Analogs
Medroxyprogesteron_acetate Brand Names Mixture
Lunelle (Medroxyprogesterone + Estradiol)
Medroxyprogesteron_acetate Chemical_Formula
C22H32O3
Medroxyprogesteron_acetate RX_link
http://www.rxlist.com/cgi/generic/medrox.htm
Medroxyprogesteron_acetate fda sheet
Medroxyprogesteron_acetate msds (material safety sheet)
Medroxyprogesteron_acetate Synthesis Reference
P. Ruggieri, C. Ferrari, U.S. Pat. 3,043,832 (1962)
Medroxyprogesteron_acetate Molecular Weight
344.488 g/mol
Medroxyprogesteron_acetate Melting Point
220 - 223.5 oC
Medroxyprogesteron_acetate H2O Solubility
22.2mg/L
Medroxyprogesteron_acetate State
Solid
Medroxyprogesteron_acetate LogP
3.606
Medroxyprogesteron_acetate Dosage Forms
Tablets; Depo injection
Medroxyprogesteron_acetate Indication
Used as a contraceptive and to treat amenorrhea, abnormal uterine bleeding, endometriosis, endometrial and renal cell carcinomas, and pulmonary disorders such as chronic obstructive pulmonary disease (COPD), Pickwickian syndrome, and other hypercapnic pulmonary conditions.
Medroxyprogesteron_acetate Pharmacology
Medroxyprogesterone is a synthetic progestin more potent than progesterone.
Medroxyprogesteron_acetate Absorption
Rapidly absorbed from GI tract
Medroxyprogesteron_acetate Toxicity
Side effects include loss of bone mineral density, BMD changes in adult women, bleeding irregularities, cancer risks, and thromboembolic disorders.
Medroxyprogesteron_acetate Patient Information
Medroxyprogesteron_acetate Organisms Affected
Humans and other mammals
