Medrossiprogesterone_[Dcit]
Category
Medrossiprogesterone_[Dcit] Brand names, Medrossiprogesterone_[Dcit] Analogs
Medrossiprogesterone_[Dcit] Brand Names Mixture
Lunelle (Medroxyprogesterone + Estradiol)
Medrossiprogesterone_[Dcit] Chemical_Formula
C22H32O3
Medrossiprogesterone_[Dcit] RX_link
http://www.rxlist.com/cgi/generic/medrox.htm
Medrossiprogesterone_[Dcit] fda sheet
Medrossiprogesterone_[Dcit] msds (material safety sheet)
Medrossiprogesterone_[Dcit] Synthesis Reference
P. Ruggieri, C. Ferrari, U.S. Pat. 3,043,832 (1962)
Medrossiprogesterone_[Dcit] Molecular Weight
344.488 g/mol
Medrossiprogesterone_[Dcit] Melting Point
220 - 223.5 oC
Medrossiprogesterone_[Dcit] H2O Solubility
22.2mg/L
Medrossiprogesterone_[Dcit] State
Solid
Medrossiprogesterone_[Dcit] LogP
3.606
Medrossiprogesterone_[Dcit] Dosage Forms
Tablets; Depo injection
Medrossiprogesterone_[Dcit] Indication
Used as a contraceptive and to treat amenorrhea, abnormal uterine bleeding, endometriosis, endometrial and renal cell carcinomas, and pulmonary disorders such as chronic obstructive pulmonary disease (COPD), Pickwickian syndrome, and other hypercapnic pulmonary conditions.
Medrossiprogesterone_[Dcit] Pharmacology
Medroxyprogesterone is a synthetic progestin more potent than progesterone.
Medrossiprogesterone_[Dcit] Absorption
Rapidly absorbed from GI tract
Medrossiprogesterone_[Dcit] Toxicity
Side effects include loss of bone mineral density, BMD changes in adult women, bleeding irregularities, cancer risks, and thromboembolic disorders.
Medrossiprogesterone_[Dcit] Patient Information
Medrossiprogesterone_[Dcit] Organisms Affected
Humans and other mammals