Depomedroxyprogesterone_acetate
Category
Depomedroxyprogesterone_acetate Brand names, Depomedroxyprogesterone_acetate Analogs
Depomedroxyprogesterone_acetate Brand Names Mixture
Lunelle (Medroxyprogesterone + Estradiol)
Depomedroxyprogesterone_acetate Chemical_Formula
C22H32O3
Depomedroxyprogesterone_acetate RX_link
http://www.rxlist.com/cgi/generic/medrox.htm
Depomedroxyprogesterone_acetate fda sheet
Depomedroxyprogesterone_acetate msds (material safety sheet)
Depomedroxyprogesterone_acetate Synthesis Reference
P. Ruggieri, C. Ferrari, U.S. Pat. 3,043,832 (1962)
Depomedroxyprogesterone_acetate Molecular Weight
344.488 g/mol
Depomedroxyprogesterone_acetate Melting Point
220 - 223.5 oC
Depomedroxyprogesterone_acetate H2O Solubility
22.2mg/L
Depomedroxyprogesterone_acetate State
Solid
Depomedroxyprogesterone_acetate LogP
3.606
Depomedroxyprogesterone_acetate Dosage Forms
Tablets; Depo injection
Depomedroxyprogesterone_acetate Indication
Used as a contraceptive and to treat amenorrhea, abnormal uterine bleeding, endometriosis, endometrial and renal cell carcinomas, and pulmonary disorders such as chronic obstructive pulmonary disease (COPD), Pickwickian syndrome, and other hypercapnic pulmonary conditions.
Depomedroxyprogesterone_acetate Pharmacology
Medroxyprogesterone is a synthetic progestin more potent than progesterone.
Depomedroxyprogesterone_acetate Absorption
Rapidly absorbed from GI tract
Depomedroxyprogesterone_acetate Toxicity
Side effects include loss of bone mineral density, BMD changes in adult women, bleeding irregularities, cancer risks, and thromboembolic disorders.
Depomedroxyprogesterone_acetate Patient Information
Depomedroxyprogesterone_acetate Organisms Affected
Humans and other mammals
