Perlutex_Leo
Category
Perlutex_Leo Brand names, Perlutex_Leo Analogs
Perlutex_Leo Brand Names Mixture
Lunelle (Medroxyprogesterone + Estradiol)
Perlutex_Leo Chemical_Formula
C22H32O3
Perlutex_Leo RX_link
http://www.rxlist.com/cgi/generic/medrox.htm
Perlutex_Leo fda sheet
Perlutex_Leo msds (material safety sheet)
Perlutex_Leo Synthesis Reference
P. Ruggieri, C. Ferrari, U.S. Pat. 3,043,832 (1962)
Perlutex_Leo Molecular Weight
344.488 g/mol
Perlutex_Leo Melting Point
220 - 223.5 oC
Perlutex_Leo H2O Solubility
22.2mg/L
Perlutex_Leo State
Solid
Perlutex_Leo LogP
3.606
Perlutex_Leo Dosage Forms
Tablets; Depo injection
Perlutex_Leo Indication
Used as a contraceptive and to treat amenorrhea, abnormal uterine bleeding, endometriosis, endometrial and renal cell carcinomas, and pulmonary disorders such as chronic obstructive pulmonary disease (COPD), Pickwickian syndrome, and other hypercapnic pulmonary conditions.
Perlutex_Leo Pharmacology
Medroxyprogesterone is a synthetic progestin more potent than progesterone.
Perlutex_Leo Absorption
Rapidly absorbed from GI tract
Perlutex_Leo Toxicity
Side effects include loss of bone mineral density, BMD changes in adult women, bleeding irregularities, cancer risks, and thromboembolic disorders.
Perlutex_Leo Patient Information
Perlutex_Leo Organisms Affected
Humans and other mammals
