Medroxyprogesteronum_[Inn-Latin]
Category
Medroxyprogesteronum_[Inn-Latin] Brand names, Medroxyprogesteronum_[Inn-Latin] Analogs
Medroxyprogesteronum_[Inn-Latin] Brand Names Mixture
Lunelle (Medroxyprogesterone + Estradiol)
Medroxyprogesteronum_[Inn-Latin] Chemical_Formula
C22H32O3
Medroxyprogesteronum_[Inn-Latin] RX_link
http://www.rxlist.com/cgi/generic/medrox.htm
Medroxyprogesteronum_[Inn-Latin] fda sheet
Medroxyprogesteronum_[Inn-Latin] msds (material safety sheet)
Medroxyprogesteronum_[Inn-Latin] Synthesis Reference
P. Ruggieri, C. Ferrari, U.S. Pat. 3,043,832 (1962)
Medroxyprogesteronum_[Inn-Latin] Molecular Weight
344.488 g/mol
Medroxyprogesteronum_[Inn-Latin] Melting Point
220 - 223.5 oC
Medroxyprogesteronum_[Inn-Latin] H2O Solubility
22.2mg/L
Medroxyprogesteronum_[Inn-Latin] State
Solid
Medroxyprogesteronum_[Inn-Latin] LogP
3.606
Medroxyprogesteronum_[Inn-Latin] Dosage Forms
Tablets; Depo injection
Medroxyprogesteronum_[Inn-Latin] Indication
Used as a contraceptive and to treat amenorrhea, abnormal uterine bleeding, endometriosis, endometrial and renal cell carcinomas, and pulmonary disorders such as chronic obstructive pulmonary disease (COPD), Pickwickian syndrome, and other hypercapnic pulmonary conditions.
Medroxyprogesteronum_[Inn-Latin] Pharmacology
Medroxyprogesterone is a synthetic progestin more potent than progesterone.
Medroxyprogesteronum_[Inn-Latin] Absorption
Rapidly absorbed from GI tract
Medroxyprogesteronum_[Inn-Latin] Toxicity
Side effects include loss of bone mineral density, BMD changes in adult women, bleeding irregularities, cancer risks, and thromboembolic disorders.
Medroxyprogesteronum_[Inn-Latin] Patient Information
Medroxyprogesteronum_[Inn-Latin] Organisms Affected
Humans and other mammals