MPA
Category
MPA Brand names, MPA Analogs
MPA Brand Names Mixture
Lunelle (Medroxyprogesterone + Estradiol)
MPA Chemical_Formula
C22H32O3
MPA RX_link
http://www.rxlist.com/cgi/generic/medrox.htm
MPA fda sheet
MPA msds (material safety sheet)
MPA Synthesis Reference
P. Ruggieri, C. Ferrari, U.S. Pat. 3,043,832 (1962)
MPA Molecular Weight
344.488 g/mol
MPA Melting Point
220 - 223.5 oC
MPA H2O Solubility
22.2mg/L
MPA State
Solid
MPA LogP
3.606
MPA Dosage Forms
Tablets; Depo injection
MPA Indication
Used as a contraceptive and to treat amenorrhea, abnormal uterine bleeding, endometriosis, endometrial and renal cell carcinomas, and pulmonary disorders such as chronic obstructive pulmonary disease (COPD), Pickwickian syndrome, and other hypercapnic pulmonary conditions.
MPA Pharmacology
Medroxyprogesterone is a synthetic progestin more potent than progesterone.
MPA Absorption
Rapidly absorbed from GI tract
MPA Toxicity
Side effects include loss of bone mineral density, BMD changes in adult women, bleeding irregularities, cancer risks, and thromboembolic disorders.
MPA Patient Information
MPA Organisms Affected
Humans and other mammals