Medroxiprogesterona_[Inn-Spanish]
Category
Medroxiprogesterona_[Inn-Spanish] Brand names, Medroxiprogesterona_[Inn-Spanish] Analogs
Medroxiprogesterona_[Inn-Spanish] Brand Names Mixture
Lunelle (Medroxyprogesterone + Estradiol)
Medroxiprogesterona_[Inn-Spanish] Chemical_Formula
C22H32O3
Medroxiprogesterona_[Inn-Spanish] RX_link
http://www.rxlist.com/cgi/generic/medrox.htm
Medroxiprogesterona_[Inn-Spanish] fda sheet
Medroxiprogesterona_[Inn-Spanish] msds (material safety sheet)
Medroxiprogesterona_[Inn-Spanish] Synthesis Reference
P. Ruggieri, C. Ferrari, U.S. Pat. 3,043,832 (1962)
Medroxiprogesterona_[Inn-Spanish] Molecular Weight
344.488 g/mol
Medroxiprogesterona_[Inn-Spanish] Melting Point
220 - 223.5 oC
Medroxiprogesterona_[Inn-Spanish] H2O Solubility
22.2mg/L
Medroxiprogesterona_[Inn-Spanish] State
Solid
Medroxiprogesterona_[Inn-Spanish] LogP
3.606
Medroxiprogesterona_[Inn-Spanish] Dosage Forms
Tablets; Depo injection
Medroxiprogesterona_[Inn-Spanish] Indication
Used as a contraceptive and to treat amenorrhea, abnormal uterine bleeding, endometriosis, endometrial and renal cell carcinomas, and pulmonary disorders such as chronic obstructive pulmonary disease (COPD), Pickwickian syndrome, and other hypercapnic pulmonary conditions.
Medroxiprogesterona_[Inn-Spanish] Pharmacology
Medroxyprogesterone is a synthetic progestin more potent than progesterone.
Medroxiprogesterona_[Inn-Spanish] Absorption
Rapidly absorbed from GI tract
Medroxiprogesterona_[Inn-Spanish] Toxicity
Side effects include loss of bone mineral density, BMD changes in adult women, bleeding irregularities, cancer risks, and thromboembolic disorders.
Medroxiprogesterona_[Inn-Spanish] Patient Information
Medroxiprogesterona_[Inn-Spanish] Organisms Affected
Humans and other mammals