Metigestrona
Category
Metigestrona Brand names, Metigestrona Analogs
Metigestrona Brand Names Mixture
Lunelle (Medroxyprogesterone + Estradiol)
Metigestrona Chemical_Formula
C22H32O3
Metigestrona RX_link
http://www.rxlist.com/cgi/generic/medrox.htm
Metigestrona fda sheet
Metigestrona msds (material safety sheet)
Metigestrona Synthesis Reference
P. Ruggieri, C. Ferrari, U.S. Pat. 3,043,832 (1962)
Metigestrona Molecular Weight
344.488 g/mol
Metigestrona Melting Point
220 - 223.5 oC
Metigestrona H2O Solubility
22.2mg/L
Metigestrona State
Solid
Metigestrona LogP
3.606
Metigestrona Dosage Forms
Tablets; Depo injection
Metigestrona Indication
Used as a contraceptive and to treat amenorrhea, abnormal uterine bleeding, endometriosis, endometrial and renal cell carcinomas, and pulmonary disorders such as chronic obstructive pulmonary disease (COPD), Pickwickian syndrome, and other hypercapnic pulmonary conditions.
Metigestrona Pharmacology
Medroxyprogesterone is a synthetic progestin more potent than progesterone.
Metigestrona Absorption
Rapidly absorbed from GI tract
Metigestrona Toxicity
Side effects include loss of bone mineral density, BMD changes in adult women, bleeding irregularities, cancer risks, and thromboembolic disorders.
Metigestrona Patient Information
Metigestrona Organisms Affected
Humans and other mammals