Medroxyprogesterone_Base
Category
Medroxyprogesterone_Base Brand names, Medroxyprogesterone_Base Analogs
Medroxyprogesterone_Base Brand Names Mixture
Lunelle (Medroxyprogesterone + Estradiol)
Medroxyprogesterone_Base Chemical_Formula
C22H32O3
Medroxyprogesterone_Base RX_link
http://www.rxlist.com/cgi/generic/medrox.htm
Medroxyprogesterone_Base fda sheet
Medroxyprogesterone_Base msds (material safety sheet)
Medroxyprogesterone_Base Synthesis Reference
P. Ruggieri, C. Ferrari, U.S. Pat. 3,043,832 (1962)
Medroxyprogesterone_Base Molecular Weight
344.488 g/mol
Medroxyprogesterone_Base Melting Point
220 - 223.5 oC
Medroxyprogesterone_Base H2O Solubility
22.2mg/L
Medroxyprogesterone_Base State
Solid
Medroxyprogesterone_Base LogP
3.606
Medroxyprogesterone_Base Dosage Forms
Tablets; Depo injection
Medroxyprogesterone_Base Indication
Used as a contraceptive and to treat amenorrhea, abnormal uterine bleeding, endometriosis, endometrial and renal cell carcinomas, and pulmonary disorders such as chronic obstructive pulmonary disease (COPD), Pickwickian syndrome, and other hypercapnic pulmonary conditions.
Medroxyprogesterone_Base Pharmacology
Medroxyprogesterone is a synthetic progestin more potent than progesterone.
Medroxyprogesterone_Base Absorption
Rapidly absorbed from GI tract
Medroxyprogesterone_Base Toxicity
Side effects include loss of bone mineral density, BMD changes in adult women, bleeding irregularities, cancer risks, and thromboembolic disorders.
Medroxyprogesterone_Base Patient Information
Medroxyprogesterone_Base Organisms Affected
Humans and other mammals
