Meprate
Category
Meprate Brand names, Meprate Analogs
Meprate Brand Names Mixture
Lunelle (Medroxyprogesterone + Estradiol)
Meprate Chemical_Formula
C22H32O3
Meprate RX_link
http://www.rxlist.com/cgi/generic/medrox.htm
Meprate fda sheet
Meprate msds (material safety sheet)
Meprate Synthesis Reference
P. Ruggieri, C. Ferrari, U.S. Pat. 3,043,832 (1962)
Meprate Molecular Weight
344.488 g/mol
Meprate Melting Point
220 - 223.5 oC
Meprate H2O Solubility
22.2mg/L
Meprate State
Solid
Meprate LogP
3.606
Meprate Dosage Forms
Tablets; Depo injection
Meprate Indication
Used as a contraceptive and to treat amenorrhea, abnormal uterine bleeding, endometriosis, endometrial and renal cell carcinomas, and pulmonary disorders such as chronic obstructive pulmonary disease (COPD), Pickwickian syndrome, and other hypercapnic pulmonary conditions.
Meprate Pharmacology
Medroxyprogesterone is a synthetic progestin more potent than progesterone.
Meprate Absorption
Rapidly absorbed from GI tract
Meprate Toxicity
Side effects include loss of bone mineral density, BMD changes in adult women, bleeding irregularities, cancer risks, and thromboembolic disorders.
Meprate Patient Information
Meprate Organisms Affected
Humans and other mammals