Nadigest
Category
Nadigest Brand names, Nadigest Analogs
Nadigest Brand Names Mixture
Lunelle (Medroxyprogesterone + Estradiol)
Nadigest Chemical_Formula
C22H32O3
Nadigest RX_link
http://www.rxlist.com/cgi/generic/medrox.htm
Nadigest fda sheet
Nadigest msds (material safety sheet)
Nadigest Synthesis Reference
P. Ruggieri, C. Ferrari, U.S. Pat. 3,043,832 (1962)
Nadigest Molecular Weight
344.488 g/mol
Nadigest Melting Point
220 - 223.5 oC
Nadigest H2O Solubility
22.2mg/L
Nadigest State
Solid
Nadigest LogP
3.606
Nadigest Dosage Forms
Tablets; Depo injection
Nadigest Indication
Used as a contraceptive and to treat amenorrhea, abnormal uterine bleeding, endometriosis, endometrial and renal cell carcinomas, and pulmonary disorders such as chronic obstructive pulmonary disease (COPD), Pickwickian syndrome, and other hypercapnic pulmonary conditions.
Nadigest Pharmacology
Medroxyprogesterone is a synthetic progestin more potent than progesterone.
Nadigest Absorption
Rapidly absorbed from GI tract
Nadigest Toxicity
Side effects include loss of bone mineral density, BMD changes in adult women, bleeding irregularities, cancer risks, and thromboembolic disorders.
Nadigest Patient Information
Nadigest Organisms Affected
Humans and other mammals