Depot-Medroxyprogesterone_acetate
Category
Depot-Medroxyprogesterone_acetate Brand names, Depot-Medroxyprogesterone_acetate Analogs
Depot-Medroxyprogesterone_acetate Brand Names Mixture
Lunelle (Medroxyprogesterone + Estradiol)
Depot-Medroxyprogesterone_acetate Chemical_Formula
C22H32O3
Depot-Medroxyprogesterone_acetate RX_link
http://www.rxlist.com/cgi/generic/medrox.htm
Depot-Medroxyprogesterone_acetate fda sheet
Depot-Medroxyprogesterone_acetate msds (material safety sheet)
Depot-Medroxyprogesterone_acetate Synthesis Reference
P. Ruggieri, C. Ferrari, U.S. Pat. 3,043,832 (1962)
Depot-Medroxyprogesterone_acetate Molecular Weight
344.488 g/mol
Depot-Medroxyprogesterone_acetate Melting Point
220 - 223.5 oC
Depot-Medroxyprogesterone_acetate H2O Solubility
22.2mg/L
Depot-Medroxyprogesterone_acetate State
Solid
Depot-Medroxyprogesterone_acetate LogP
3.606
Depot-Medroxyprogesterone_acetate Dosage Forms
Tablets; Depo injection
Depot-Medroxyprogesterone_acetate Indication
Used as a contraceptive and to treat amenorrhea, abnormal uterine bleeding, endometriosis, endometrial and renal cell carcinomas, and pulmonary disorders such as chronic obstructive pulmonary disease (COPD), Pickwickian syndrome, and other hypercapnic pulmonary conditions.
Depot-Medroxyprogesterone_acetate Pharmacology
Medroxyprogesterone is a synthetic progestin more potent than progesterone.
Depot-Medroxyprogesterone_acetate Absorption
Rapidly absorbed from GI tract
Depot-Medroxyprogesterone_acetate Toxicity
Side effects include loss of bone mineral density, BMD changes in adult women, bleeding irregularities, cancer risks, and thromboembolic disorders.
Depot-Medroxyprogesterone_acetate Patient Information
Depot-Medroxyprogesterone_acetate Organisms Affected
Humans and other mammals
