Trimethoprim
Brand names,
Trimethoprim
Analogs
Trimethoprim
Brand Names Mixture
Trimethoprim
Chemical_Formula
C14H18N4O3
Trimethoprim
RX_link
http://www.rxlist.com/cgi/generic2/trimeth.htm
Trimethoprim
fda sheet
Trimethoprim
msds (material safety sheet)
Trimethoprim
Synthesis Reference
Hook, U.S. Pat. 3,049,544 (1962)
Trimethoprim
Molecular Weight
290.318 g/mol
Trimethoprim
Melting Point
199 - 203 oC
Trimethoprim
H2O Solubility
12.1 mg/mL
Trimethoprim
State
Solid
Trimethoprim
LogP
1.364
Trimethoprim
Dosage Forms
Tablet
Trimethoprim
Indication
For the treatment of initial episodes of uncomplicated urinary tract infections
Trimethoprim
Pharmacology
Trimethoprim, a synthetic antiinfective agent, is used to treat and prevent urinary tract infections, diarrhea, and, when combined with either sulfamethoxazole or dapsone, Pneumocystis carinii infections.
Trimethoprim
Absorption
No information avaliable
Trimethoprim
side effects and Toxicity
LD50=4850 (orally in mice)
Trimethoprim
Patient Information
No information avaliable
Trimethoprim
Organisms Affected
Gram negative and gram positive bacteria