Trimethopriom
Brand names,
Trimethopriom
Analogs
Trimethopriom
Brand Names Mixture
Trimethopriom
Chemical_Formula
C14H18N4O3
Trimethopriom
RX_link
http://www.rxlist.com/cgi/generic2/trimeth.htm
Trimethopriom
fda sheet
Trimethopriom
msds (material safety sheet)
Trimethopriom
Synthesis Reference
Hook, U.S. Pat. 3,049,544 (1962)
Trimethopriom
Molecular Weight
290.318 g/mol
Trimethopriom
Melting Point
199 - 203 oC
Trimethopriom
H2O Solubility
12.1 mg/mL
Trimethopriom
State
Solid
Trimethopriom
LogP
1.364
Trimethopriom
Dosage Forms
Tablet
Trimethopriom
Indication
For the treatment of initial episodes of uncomplicated urinary tract infections
Trimethopriom
Pharmacology
Trimethoprim, a synthetic antiinfective agent, is used to treat and prevent urinary tract infections, diarrhea, and, when combined with either sulfamethoxazole or dapsone, Pneumocystis carinii infections.
Trimethopriom
Absorption
No information avaliable
Trimethopriom
side effects and Toxicity
LD50=4850 (orally in mice)
Trimethopriom
Patient Information
No information avaliable
Trimethopriom
Organisms Affected
Gram negative and gram positive bacteria