Trimetoprim
Brand names,
Trimetoprim
Analogs
Trimetoprim
Brand Names Mixture
Trimetoprim
Chemical_Formula
C14H18N4O3
Trimetoprim
RX_link
http://www.rxlist.com/cgi/generic2/trimeth.htm
Trimetoprim
fda sheet
Trimetoprim
msds (material safety sheet)
Trimetoprim
Synthesis Reference
Hook, U.S. Pat. 3,049,544 (1962)
Trimetoprim
Molecular Weight
290.318 g/mol
Trimetoprim
Melting Point
199 - 203 oC
Trimetoprim
H2O Solubility
12.1 mg/mL
Trimetoprim
State
Solid
Trimetoprim
LogP
1.364
Trimetoprim
Dosage Forms
Tablet
Trimetoprim
Indication
For the treatment of initial episodes of uncomplicated urinary tract infections
Trimetoprim
Pharmacology
Trimethoprim, a synthetic antiinfective agent, is used to treat and prevent urinary tract infections, diarrhea, and, when combined with either sulfamethoxazole or dapsone, Pneumocystis carinii infections.
Trimetoprim
Absorption
No information avaliable
Trimetoprim
side effects and Toxicity
LD50=4850 (orally in mice)
Trimetoprim
Patient Information
No information avaliable
Trimetoprim
Organisms Affected
Gram negative and gram positive bacteria