Methoprim
Brand names,
Methoprim
Analogs
Methoprim
Brand Names Mixture
Methoprim
Chemical_Formula
C14H18N4O3
Methoprim
RX_link
http://www.rxlist.com/cgi/generic2/trimeth.htm
Methoprim
fda sheet
Methoprim
msds (material safety sheet)
Methoprim
Synthesis Reference
Hook, U.S. Pat. 3,049,544 (1962)
Methoprim
Molecular Weight
290.318 g/mol
Methoprim
Melting Point
199 - 203 oC
Methoprim
H2O Solubility
12.1 mg/mL
Methoprim
State
Solid
Methoprim
LogP
1.364
Methoprim
Dosage Forms
Tablet
Methoprim
Indication
For the treatment of initial episodes of uncomplicated urinary tract infections
Methoprim
Pharmacology
Trimethoprim, a synthetic antiinfective agent, is used to treat and prevent urinary tract infections, diarrhea, and, when combined with either sulfamethoxazole or dapsone, Pneumocystis carinii infections.
Methoprim
Absorption
No information avaliable
Methoprim
side effects and Toxicity
LD50=4850 (orally in mice)
Methoprim
Patient Information
No information avaliable
Methoprim
Organisms Affected
Gram negative and gram positive bacteria