Supracombin
Brand names,
Supracombin
Analogs
Supracombin
Brand Names Mixture
Supracombin
Chemical_Formula
C14H18N4O3
Supracombin
RX_link
http://www.rxlist.com/cgi/generic2/trimeth.htm
Supracombin
fda sheet
Supracombin
msds (material safety sheet)
Supracombin
Synthesis Reference
Hook, U.S. Pat. 3,049,544 (1962)
Supracombin
Molecular Weight
290.318 g/mol
Supracombin
Melting Point
199 - 203 oC
Supracombin
H2O Solubility
12.1 mg/mL
Supracombin
State
Solid
Supracombin
LogP
1.364
Supracombin
Dosage Forms
Tablet
Supracombin
Indication
For the treatment of initial episodes of uncomplicated urinary tract infections
Supracombin
Pharmacology
Trimethoprim, a synthetic antiinfective agent, is used to treat and prevent urinary tract infections, diarrhea, and, when combined with either sulfamethoxazole or dapsone, Pneumocystis carinii infections.
Supracombin
Absorption
No information avaliable
Supracombin
side effects and Toxicity
LD50=4850 (orally in mice)
Supracombin
Patient Information
No information avaliable
Supracombin
Organisms Affected
Gram negative and gram positive bacteria