Trimethioprim
Brand names,
Trimethioprim
Analogs
Trimethioprim
Brand Names Mixture
Trimethioprim
Chemical_Formula
C14H18N4O3
Trimethioprim
RX_link
http://www.rxlist.com/cgi/generic2/trimeth.htm
Trimethioprim
fda sheet
Trimethioprim
msds (material safety sheet)
Trimethioprim
Synthesis Reference
Hook, U.S. Pat. 3,049,544 (1962)
Trimethioprim
Molecular Weight
290.318 g/mol
Trimethioprim
Melting Point
199 - 203 oC
Trimethioprim
H2O Solubility
12.1 mg/mL
Trimethioprim
State
Solid
Trimethioprim
LogP
1.364
Trimethioprim
Dosage Forms
Tablet
Trimethioprim
Indication
For the treatment of initial episodes of uncomplicated urinary tract infections
Trimethioprim
Pharmacology
Trimethoprim, a synthetic antiinfective agent, is used to treat and prevent urinary tract infections, diarrhea, and, when combined with either sulfamethoxazole or dapsone, Pneumocystis carinii infections.
Trimethioprim
Absorption
No information avaliable
Trimethioprim
side effects and Toxicity
LD50=4850 (orally in mice)
Trimethioprim
Patient Information
No information avaliable
Trimethioprim
Organisms Affected
Gram negative and gram positive bacteria