Sigaprim
Brand names,
Sigaprim
Analogs
Sigaprim
Brand Names Mixture
Sigaprim
Chemical_Formula
C14H18N4O3
Sigaprim
RX_link
http://www.rxlist.com/cgi/generic2/trimeth.htm
Sigaprim
fda sheet
Sigaprim
msds (material safety sheet)
Sigaprim
Synthesis Reference
Hook, U.S. Pat. 3,049,544 (1962)
Sigaprim
Molecular Weight
290.318 g/mol
Sigaprim
Melting Point
199 - 203 oC
Sigaprim
H2O Solubility
12.1 mg/mL
Sigaprim
State
Solid
Sigaprim
LogP
1.364
Sigaprim
Dosage Forms
Tablet
Sigaprim
Indication
For the treatment of initial episodes of uncomplicated urinary tract infections
Sigaprim
Pharmacology
Trimethoprim, a synthetic antiinfective agent, is used to treat and prevent urinary tract infections, diarrhea, and, when combined with either sulfamethoxazole or dapsone, Pneumocystis carinii infections.
Sigaprim
Absorption
No information avaliable
Sigaprim
side effects and Toxicity
LD50=4850 (orally in mice)
Sigaprim
Patient Information
No information avaliable
Sigaprim
Organisms Affected
Gram negative and gram positive bacteria