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Brand names,
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Analogs
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Brand Names Mixture
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Chemical_Formula
C14H18N4O3
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RX_link
http://www.rxlist.com/cgi/generic2/trimeth.htm
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
Hook, U.S. Pat. 3,049,544 (1962)
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Molecular Weight
290.318 g/mol
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Melting Point
199 - 203 oC
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H2O Solubility
12.1 mg/mL
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State
Solid
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LogP
1.364
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Dosage Forms
Tablet
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Indication
For the treatment of initial episodes of uncomplicated urinary tract infections
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Pharmacology
Trimethoprim, a synthetic antiinfective agent, is used to treat and prevent urinary tract infections, diarrhea, and, when combined with either sulfamethoxazole or dapsone, Pneumocystis carinii infections.
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Absorption
No information avaliable
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side effects and Toxicity
LD50=4850 (orally in mice)
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Patient Information
No information avaliable
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Organisms Affected
Gram negative and gram positive bacteria