Sulfamethoxazole & Trimethoprim
Brand names,
Sulfamethoxazole & Trimethoprim
Analogs
Sulfamethoxazole & Trimethoprim
Brand Names Mixture
Sulfamethoxazole & Trimethoprim
Chemical_Formula
C14H18N4O3
Sulfamethoxazole & Trimethoprim
RX_link
http://www.rxlist.com/cgi/generic2/trimeth.htm
Sulfamethoxazole & Trimethoprim
fda sheet
Sulfamethoxazole & Trimethoprim
msds (material safety sheet)
Sulfamethoxazole & Trimethoprim
Synthesis Reference
Hook, U.S. Pat. 3,049,544 (1962)
Sulfamethoxazole & Trimethoprim
Molecular Weight
290.318 g/mol
Sulfamethoxazole & Trimethoprim
Melting Point
199 - 203 oC
Sulfamethoxazole & Trimethoprim
H2O Solubility
12.1 mg/mL
Sulfamethoxazole & Trimethoprim
State
Solid
Sulfamethoxazole & Trimethoprim
LogP
1.364
Sulfamethoxazole & Trimethoprim
Dosage Forms
Tablet
Sulfamethoxazole & Trimethoprim
Indication
For the treatment of initial episodes of uncomplicated urinary tract infections
Sulfamethoxazole & Trimethoprim
Pharmacology
Trimethoprim, a synthetic antiinfective agent, is used to treat and prevent urinary tract infections, diarrhea, and, when combined with either sulfamethoxazole or dapsone, Pneumocystis carinii infections.
Sulfamethoxazole & Trimethoprim
Absorption
No information avaliable
Sulfamethoxazole & Trimethoprim
side effects and Toxicity
LD50=4850 (orally in mice)
Sulfamethoxazole & Trimethoprim
Patient Information
No information avaliable
Sulfamethoxazole & Trimethoprim
Organisms Affected
Gram negative and gram positive bacteria