Trimeth/Sulfa
Brand names,
Trimeth/Sulfa
Analogs
Trimeth/Sulfa
Brand Names Mixture
Trimeth/Sulfa
Chemical_Formula
C14H18N4O3
Trimeth/Sulfa
RX_link
http://www.rxlist.com/cgi/generic2/trimeth.htm
Trimeth/Sulfa
fda sheet
Trimeth/Sulfa
msds (material safety sheet)
Trimeth/Sulfa
Synthesis Reference
Hook, U.S. Pat. 3,049,544 (1962)
Trimeth/Sulfa
Molecular Weight
290.318 g/mol
Trimeth/Sulfa
Melting Point
199 - 203 oC
Trimeth/Sulfa
H2O Solubility
12.1 mg/mL
Trimeth/Sulfa
State
Solid
Trimeth/Sulfa
LogP
1.364
Trimeth/Sulfa
Dosage Forms
Tablet
Trimeth/Sulfa
Indication
For the treatment of initial episodes of uncomplicated urinary tract infections
Trimeth/Sulfa
Pharmacology
Trimethoprim, a synthetic antiinfective agent, is used to treat and prevent urinary tract infections, diarrhea, and, when combined with either sulfamethoxazole or dapsone, Pneumocystis carinii infections.
Trimeth/Sulfa
Absorption
No information avaliable
Trimeth/Sulfa
side effects and Toxicity
LD50=4850 (orally in mice)
Trimeth/Sulfa
Patient Information
No information avaliable
Trimeth/Sulfa
Organisms Affected
Gram negative and gram positive bacteria