Syntexan
Brand names,
Syntexan
Analogs
Syntexan
Brand Names Mixture
- Rifater - Tab (Isoniazid + Pyrazinamide + Rifampin)
Syntexan
Chemical_Formula
C2H6OS
Syntexan
RX_link
http://www.rxlist.com/cgi/generic2/dmso.htm
Syntexan
fda sheet
Syntexan
msds (material safety sheet)
Syntexan
Synthesis Reference
No information avaliable
Syntexan
Molecular Weight
78.1344 g/mol
Syntexan
Melting Point
18.5 oC
Syntexan
H2O Solubility
1E+006 mg/L
Syntexan
State
Liquid
Syntexan
LogP
-1.082
Syntexan
Dosage Forms
Cream (70%); Gel (70%, 90%); Injection (50%, 100%); Liquid (99%, 90%, 70%); Solution (50%)
Syntexan
Indication
For the symptomatic relief of patients with interstitial cystitis.
Syntexan
Pharmacology
Dimethyl Sulfoxide may have anti-inflammatory, antioxidant and analgesic activities. Dimethyl Sulfoxide also readily penetrates cellular membranes. The membrane-penetrating ability of dimethyl sulfoxide may enhance diffusion of other substances through the skin. For this reason, mixtures of idoxuridine and dimethyl sulfoxide have been used for topical treatment of herpes zoster in the United Kingdom.
Syntexan
Absorption
Readily and rapidly absorbed following administration by all routes and distributed throughout the body.
Syntexan
side effects and Toxicity
The oral LD50 of dimethyl sulfoxide in the dog is greater than 10 gm/kg. It is improbable that this dosage level could be obtained with intravesical instillation of dimethyl sulfoxide in the patient.
Syntexan
Patient Information
Syntexan
Organisms Affected
Humans and other mammals