Dolicur
Brand names,
Dolicur
Analogs
Dolicur
Brand Names Mixture
- Rifater - Tab (Isoniazid + Pyrazinamide + Rifampin)
Dolicur
Chemical_Formula
C2H6OS
Dolicur
RX_link
http://www.rxlist.com/cgi/generic2/dmso.htm
Dolicur
fda sheet
Dolicur
msds (material safety sheet)
Dolicur
Synthesis Reference
No information avaliable
Dolicur
Molecular Weight
78.1344 g/mol
Dolicur
Melting Point
18.5 oC
Dolicur
H2O Solubility
1E+006 mg/L
Dolicur
State
Liquid
Dolicur
LogP
-1.082
Dolicur
Dosage Forms
Cream (70%); Gel (70%, 90%); Injection (50%, 100%); Liquid (99%, 90%, 70%); Solution (50%)
Dolicur
Indication
For the symptomatic relief of patients with interstitial cystitis.
Dolicur
Pharmacology
Dimethyl Sulfoxide may have anti-inflammatory, antioxidant and analgesic activities. Dimethyl Sulfoxide also readily penetrates cellular membranes. The membrane-penetrating ability of dimethyl sulfoxide may enhance diffusion of other substances through the skin. For this reason, mixtures of idoxuridine and dimethyl sulfoxide have been used for topical treatment of herpes zoster in the United Kingdom.
Dolicur
Absorption
Readily and rapidly absorbed following administration by all routes and distributed throughout the body.
Dolicur
side effects and Toxicity
The oral LD50 of dimethyl sulfoxide in the dog is greater than 10 gm/kg. It is improbable that this dosage level could be obtained with intravesical instillation of dimethyl sulfoxide in the patient.
Dolicur
Patient Information
Dolicur
Organisms Affected
Humans and other mammals