Dimethyl sulfoxide BP
Brand names,
Dimethyl sulfoxide BP
Analogs
Dimethyl sulfoxide BP
Brand Names Mixture
- Rifater - Tab (Isoniazid + Pyrazinamide + Rifampin)
Dimethyl sulfoxide BP
Chemical_Formula
C2H6OS
Dimethyl sulfoxide BP
RX_link
http://www.rxlist.com/cgi/generic2/dmso.htm
Dimethyl sulfoxide BP
fda sheet
Dimethyl sulfoxide BP
msds (material safety sheet)
Dimethyl sulfoxide BP
Synthesis Reference
No information avaliable
Dimethyl sulfoxide BP
Molecular Weight
78.1344 g/mol
Dimethyl sulfoxide BP
Melting Point
18.5 oC
Dimethyl sulfoxide BP
H2O Solubility
1E+006 mg/L
Dimethyl sulfoxide BP
State
Liquid
Dimethyl sulfoxide BP
LogP
-1.082
Dimethyl sulfoxide BP
Dosage Forms
Cream (70%); Gel (70%, 90%); Injection (50%, 100%); Liquid (99%, 90%, 70%); Solution (50%)
Dimethyl sulfoxide BP
Indication
For the symptomatic relief of patients with interstitial cystitis.
Dimethyl sulfoxide BP
Pharmacology
Dimethyl Sulfoxide may have anti-inflammatory, antioxidant and analgesic activities. Dimethyl Sulfoxide also readily penetrates cellular membranes. The membrane-penetrating ability of dimethyl sulfoxide may enhance diffusion of other substances through the skin. For this reason, mixtures of idoxuridine and dimethyl sulfoxide have been used for topical treatment of herpes zoster in the United Kingdom.
Dimethyl sulfoxide BP
Absorption
Readily and rapidly absorbed following administration by all routes and distributed throughout the body.
Dimethyl sulfoxide BP
side effects and Toxicity
The oral LD50 of dimethyl sulfoxide in the dog is greater than 10 gm/kg. It is improbable that this dosage level could be obtained with intravesical instillation of dimethyl sulfoxide in the patient.
Dimethyl sulfoxide BP
Patient Information
Dimethyl sulfoxide BP
Organisms Affected
Humans and other mammals