Methylsulfinylmethane
Brand names,
Methylsulfinylmethane
Analogs
Methylsulfinylmethane
Brand Names Mixture
- Rifater - Tab (Isoniazid + Pyrazinamide + Rifampin)
Methylsulfinylmethane
Chemical_Formula
C2H6OS
Methylsulfinylmethane
RX_link
http://www.rxlist.com/cgi/generic2/dmso.htm
Methylsulfinylmethane
fda sheet
Methylsulfinylmethane
msds (material safety sheet)
Methylsulfinylmethane
Synthesis Reference
No information avaliable
Methylsulfinylmethane
Molecular Weight
78.1344 g/mol
Methylsulfinylmethane
Melting Point
18.5 oC
Methylsulfinylmethane
H2O Solubility
1E+006 mg/L
Methylsulfinylmethane
State
Liquid
Methylsulfinylmethane
LogP
-1.082
Methylsulfinylmethane
Dosage Forms
Cream (70%); Gel (70%, 90%); Injection (50%, 100%); Liquid (99%, 90%, 70%); Solution (50%)
Methylsulfinylmethane
Indication
For the symptomatic relief of patients with interstitial cystitis.
Methylsulfinylmethane
Pharmacology
Dimethyl Sulfoxide may have anti-inflammatory, antioxidant and analgesic activities. Dimethyl Sulfoxide also readily penetrates cellular membranes. The membrane-penetrating ability of dimethyl sulfoxide may enhance diffusion of other substances through the skin. For this reason, mixtures of idoxuridine and dimethyl sulfoxide have been used for topical treatment of herpes zoster in the United Kingdom.
Methylsulfinylmethane
Absorption
Readily and rapidly absorbed following administration by all routes and distributed throughout the body.
Methylsulfinylmethane
side effects and Toxicity
The oral LD50 of dimethyl sulfoxide in the dog is greater than 10 gm/kg. It is improbable that this dosage level could be obtained with intravesical instillation of dimethyl sulfoxide in the patient.
Methylsulfinylmethane
Patient Information
Methylsulfinylmethane
Organisms Affected
Humans and other mammals