Dimexidum
Brand names,
Dimexidum
Analogs
Dimexidum
Brand Names Mixture
- Rifater - Tab (Isoniazid + Pyrazinamide + Rifampin)
Dimexidum
Chemical_Formula
C2H6OS
Dimexidum
RX_link
http://www.rxlist.com/cgi/generic2/dmso.htm
Dimexidum
fda sheet
Dimexidum
msds (material safety sheet)
Dimexidum
Synthesis Reference
No information avaliable
Dimexidum
Molecular Weight
78.1344 g/mol
Dimexidum
Melting Point
18.5 oC
Dimexidum
H2O Solubility
1E+006 mg/L
Dimexidum
State
Liquid
Dimexidum
LogP
-1.082
Dimexidum
Dosage Forms
Cream (70%); Gel (70%, 90%); Injection (50%, 100%); Liquid (99%, 90%, 70%); Solution (50%)
Dimexidum
Indication
For the symptomatic relief of patients with interstitial cystitis.
Dimexidum
Pharmacology
Dimethyl Sulfoxide may have anti-inflammatory, antioxidant and analgesic activities. Dimethyl Sulfoxide also readily penetrates cellular membranes. The membrane-penetrating ability of dimethyl sulfoxide may enhance diffusion of other substances through the skin. For this reason, mixtures of idoxuridine and dimethyl sulfoxide have been used for topical treatment of herpes zoster in the United Kingdom.
Dimexidum
Absorption
Readily and rapidly absorbed following administration by all routes and distributed throughout the body.
Dimexidum
side effects and Toxicity
The oral LD50 of dimethyl sulfoxide in the dog is greater than 10 gm/kg. It is improbable that this dosage level could be obtained with intravesical instillation of dimethyl sulfoxide in the patient.
Dimexidum
Patient Information
Dimexidum
Organisms Affected
Humans and other mammals