Dimexide
Brand names,
Dimexide
Analogs
Dimexide
Brand Names Mixture
- Rifater - Tab (Isoniazid + Pyrazinamide + Rifampin)
Dimexide
Chemical_Formula
C2H6OS
Dimexide
RX_link
http://www.rxlist.com/cgi/generic2/dmso.htm
Dimexide
fda sheet
Dimexide
msds (material safety sheet)
Dimexide
Synthesis Reference
No information avaliable
Dimexide
Molecular Weight
78.1344 g/mol
Dimexide
Melting Point
18.5 oC
Dimexide
H2O Solubility
1E+006 mg/L
Dimexide
State
Liquid
Dimexide
LogP
-1.082
Dimexide
Dosage Forms
Cream (70%); Gel (70%, 90%); Injection (50%, 100%); Liquid (99%, 90%, 70%); Solution (50%)
Dimexide
Indication
For the symptomatic relief of patients with interstitial cystitis.
Dimexide
Pharmacology
Dimethyl Sulfoxide may have anti-inflammatory, antioxidant and analgesic activities. Dimethyl Sulfoxide also readily penetrates cellular membranes. The membrane-penetrating ability of dimethyl sulfoxide may enhance diffusion of other substances through the skin. For this reason, mixtures of idoxuridine and dimethyl sulfoxide have been used for topical treatment of herpes zoster in the United Kingdom.
Dimexide
Absorption
Readily and rapidly absorbed following administration by all routes and distributed throughout the body.
Dimexide
side effects and Toxicity
The oral LD50 of dimethyl sulfoxide in the dog is greater than 10 gm/kg. It is improbable that this dosage level could be obtained with intravesical instillation of dimethyl sulfoxide in the patient.
Dimexide
Patient Information
Dimexide
Organisms Affected
Humans and other mammals