Sulfoxide, dimethyl
Brand names,
Sulfoxide, dimethyl
Analogs
Sulfoxide, dimethyl
Brand Names Mixture
- Rifater - Tab (Isoniazid + Pyrazinamide + Rifampin)
Sulfoxide, dimethyl
Chemical_Formula
C2H6OS
Sulfoxide, dimethyl
RX_link
http://www.rxlist.com/cgi/generic2/dmso.htm
Sulfoxide, dimethyl
fda sheet
Sulfoxide, dimethyl
msds (material safety sheet)
Sulfoxide, dimethyl
Synthesis Reference
No information avaliable
Sulfoxide, dimethyl
Molecular Weight
78.1344 g/mol
Sulfoxide, dimethyl
Melting Point
18.5 oC
Sulfoxide, dimethyl
H2O Solubility
1E+006 mg/L
Sulfoxide, dimethyl
State
Liquid
Sulfoxide, dimethyl
LogP
-1.082
Sulfoxide, dimethyl
Dosage Forms
Cream (70%); Gel (70%, 90%); Injection (50%, 100%); Liquid (99%, 90%, 70%); Solution (50%)
Sulfoxide, dimethyl
Indication
For the symptomatic relief of patients with interstitial cystitis.
Sulfoxide, dimethyl
Pharmacology
Dimethyl Sulfoxide may have anti-inflammatory, antioxidant and analgesic activities. Dimethyl Sulfoxide also readily penetrates cellular membranes. The membrane-penetrating ability of dimethyl sulfoxide may enhance diffusion of other substances through the skin. For this reason, mixtures of idoxuridine and dimethyl sulfoxide have been used for topical treatment of herpes zoster in the United Kingdom.
Sulfoxide, dimethyl
Absorption
Readily and rapidly absorbed following administration by all routes and distributed throughout the body.
Sulfoxide, dimethyl
side effects and Toxicity
The oral LD50 of dimethyl sulfoxide in the dog is greater than 10 gm/kg. It is improbable that this dosage level could be obtained with intravesical instillation of dimethyl sulfoxide in the patient.
Sulfoxide, dimethyl
Patient Information
Sulfoxide, dimethyl
Organisms Affected
Humans and other mammals