Somipront
Brand names,
Somipront
Analogs
Somipront
Brand Names Mixture
- Rifater - Tab (Isoniazid + Pyrazinamide + Rifampin)
Somipront
Chemical_Formula
C2H6OS
Somipront
RX_link
http://www.rxlist.com/cgi/generic2/dmso.htm
Somipront
fda sheet
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msds (material safety sheet)
Somipront
Synthesis Reference
No information avaliable
Somipront
Molecular Weight
78.1344 g/mol
Somipront
Melting Point
18.5 oC
Somipront
H2O Solubility
1E+006 mg/L
Somipront
State
Liquid
Somipront
LogP
-1.082
Somipront
Dosage Forms
Cream (70%); Gel (70%, 90%); Injection (50%, 100%); Liquid (99%, 90%, 70%); Solution (50%)
Somipront
Indication
For the symptomatic relief of patients with interstitial cystitis.
Somipront
Pharmacology
Dimethyl Sulfoxide may have anti-inflammatory, antioxidant and analgesic activities. Dimethyl Sulfoxide also readily penetrates cellular membranes. The membrane-penetrating ability of dimethyl sulfoxide may enhance diffusion of other substances through the skin. For this reason, mixtures of idoxuridine and dimethyl sulfoxide have been used for topical treatment of herpes zoster in the United Kingdom.
Somipront
Absorption
Readily and rapidly absorbed following administration by all routes and distributed throughout the body.
Somipront
side effects and Toxicity
The oral LD50 of dimethyl sulfoxide in the dog is greater than 10 gm/kg. It is improbable that this dosage level could be obtained with intravesical instillation of dimethyl sulfoxide in the patient.
Somipront
Patient Information
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Organisms Affected
Humans and other mammals