Demsodrox
Brand names,
Demsodrox
Analogs
Demsodrox
Brand Names Mixture
- Rifater - Tab (Isoniazid + Pyrazinamide + Rifampin)
Demsodrox
Chemical_Formula
C2H6OS
Demsodrox
RX_link
http://www.rxlist.com/cgi/generic2/dmso.htm
Demsodrox
fda sheet
Demsodrox
msds (material safety sheet)
Demsodrox
Synthesis Reference
No information avaliable
Demsodrox
Molecular Weight
78.1344 g/mol
Demsodrox
Melting Point
18.5 oC
Demsodrox
H2O Solubility
1E+006 mg/L
Demsodrox
State
Liquid
Demsodrox
LogP
-1.082
Demsodrox
Dosage Forms
Cream (70%); Gel (70%, 90%); Injection (50%, 100%); Liquid (99%, 90%, 70%); Solution (50%)
Demsodrox
Indication
For the symptomatic relief of patients with interstitial cystitis.
Demsodrox
Pharmacology
Dimethyl Sulfoxide may have anti-inflammatory, antioxidant and analgesic activities. Dimethyl Sulfoxide also readily penetrates cellular membranes. The membrane-penetrating ability of dimethyl sulfoxide may enhance diffusion of other substances through the skin. For this reason, mixtures of idoxuridine and dimethyl sulfoxide have been used for topical treatment of herpes zoster in the United Kingdom.
Demsodrox
Absorption
Readily and rapidly absorbed following administration by all routes and distributed throughout the body.
Demsodrox
side effects and Toxicity
The oral LD50 of dimethyl sulfoxide in the dog is greater than 10 gm/kg. It is improbable that this dosage level could be obtained with intravesical instillation of dimethyl sulfoxide in the patient.
Demsodrox
Patient Information
Demsodrox
Organisms Affected
Humans and other mammals