Sclerosol
Brand names,
Sclerosol
Analogs
Sclerosol
Brand Names Mixture
- Rifater - Tab (Isoniazid + Pyrazinamide + Rifampin)
Sclerosol
Chemical_Formula
C2H6OS
Sclerosol
RX_link
http://www.rxlist.com/cgi/generic2/dmso.htm
Sclerosol
fda sheet
Sclerosol
msds (material safety sheet)
Sclerosol
Synthesis Reference
No information avaliable
Sclerosol
Molecular Weight
78.1344 g/mol
Sclerosol
Melting Point
18.5 oC
Sclerosol
H2O Solubility
1E+006 mg/L
Sclerosol
State
Liquid
Sclerosol
LogP
-1.082
Sclerosol
Dosage Forms
Cream (70%); Gel (70%, 90%); Injection (50%, 100%); Liquid (99%, 90%, 70%); Solution (50%)
Sclerosol
Indication
For the symptomatic relief of patients with interstitial cystitis.
Sclerosol
Pharmacology
Dimethyl Sulfoxide may have anti-inflammatory, antioxidant and analgesic activities. Dimethyl Sulfoxide also readily penetrates cellular membranes. The membrane-penetrating ability of dimethyl sulfoxide may enhance diffusion of other substances through the skin. For this reason, mixtures of idoxuridine and dimethyl sulfoxide have been used for topical treatment of herpes zoster in the United Kingdom.
Sclerosol
Absorption
Readily and rapidly absorbed following administration by all routes and distributed throughout the body.
Sclerosol
side effects and Toxicity
The oral LD50 of dimethyl sulfoxide in the dog is greater than 10 gm/kg. It is improbable that this dosage level could be obtained with intravesical instillation of dimethyl sulfoxide in the patient.
Sclerosol
Patient Information
Sclerosol
Organisms Affected
Humans and other mammals