Silibrin

Silibrin Brand names, Silibrin Analogs

Silibrin Brand Names Mixture

Apo-Chlorax Cap (Chlordiazepoxide Hydrochloride + Clidinium Bromide)
Corium Cap (Chlordiazepoxide Hydrochloride + Clidinium Bromide)
Librax (Chlordiazepoxide Hydrochloride + Clidinium Bromide)
Pro Chlorax (Chlordiazepoxide Hydrochloride + Clidinium Bromide)

Silibrin Chemical_Formula

C₁₆H₁₄ClN₃O

Silibrin RX_link

http://www.rxlist.com/cgi/generic/chlordia.htm

Silibrin fda sheet

Silibrin msds (material safety sheet)

Silibrin MSDS

Silibrin Synthesis Reference

No information avaliable

Silibrin Molecular Weight

299.755 g/mol

Silibrin Melting Point

236.2 ^oC

Silibrin H₂O Solubility

2000 mg/L

Silibrin State

Solid

Silibrin LogP

2.853

Silibrin Dosage Forms

Capsule (5 mg, 10 mg or 25 mg)

Silibrin Indication

For the management of anxiety disorders or for the short-term relief of symptoms of anxiety, withdrawal symptoms of acute alcoholism, and preoperative apprehension and anxiety.

Silibrin Pharmacology

Chlordiazepoxide has antianxiety, sedative, appetite-stimulating and weak analgesic actions. The precise mechanism of action is not known. The drug blocks EEG arousal from stimulation of the brain stem reticular formation. The drug has been studied extensively in many species of animals and these studies are suggestive of action on the limbic system of the brain, which recent evidence indicates is involved in emotional responses. Hostile monkeys were made tame by oral drug doses which did not cause sedation. Chlordiazepoxide revealed a "taming" action with the elimination of fear and aggression. The taming effect of chlordiazepoxide was further demonstrated in rats made vicious by lesions in the septal area of the brain. The drug dosage which effectively blocked the vicious reaction was well below the dose which caused sedation in these animals.

Silibrin Absorption