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Mesural Brand names, Mesural Analogs

Mesural Brand Names Mixture

  • Apo-Chlorax Cap (Chlordiazepoxide Hydrochloride + Clidinium Bromide)
  • Corium Cap (Chlordiazepoxide Hydrochloride + Clidinium Bromide)
  • Librax (Chlordiazepoxide Hydrochloride + Clidinium Bromide)
  • Pro Chlorax (Chlordiazepoxide Hydrochloride + Clidinium Bromide)

Mesural Chemical_Formula

C16H14ClN3O

Mesural RX_link

http://www.rxlist.com/cgi/generic/chlordia.htm

Mesural fda sheet

Mesural msds (material safety sheet)

Mesural MSDS

Mesural Synthesis Reference

No information avaliable

Mesural Molecular Weight

299.755 g/mol

Mesural Melting Point

236.2 oC

Mesural H2O Solubility

2000 mg/L

Mesural State

Solid

Mesural LogP

2.853

Mesural Dosage Forms

Capsule (5 mg, 10 mg or 25 mg)

Mesural Indication

For the management of anxiety disorders or for the short-term relief of symptoms of anxiety, withdrawal symptoms of acute alcoholism, and preoperative apprehension and anxiety.

Mesural Pharmacology

Chlordiazepoxide has antianxiety, sedative, appetite-stimulating and weak analgesic actions. The precise mechanism of action is not known. The drug blocks EEG arousal from stimulation of the brain stem reticular formation. The drug has been studied extensively in many species of animals and these studies are suggestive of action on the limbic system of the brain, which recent evidence indicates is involved in emotional responses. Hostile monkeys were made tame by oral drug doses which did not cause sedation. Chlordiazepoxide revealed a "taming" action with the elimination of fear and aggression. The taming effect of chlordiazepoxide was further demonstrated in rats made vicious by lesions in the septal area of the brain. The drug dosage which effectively blocked the vicious reaction was well below the dose which caused sedation in these animals.

Mesural Absorption

No information avaliable

Mesural side effects and Toxicity

LD50=537 mg/kg (Orally in rats). Signs of overdose include respiratory depression, muscle weakness, somnolence (general depressed activity).

Mesural Patient Information

Mesural Organisms Affected

Humans and other mammals